Royal Air Force Typhoon fighter aircraft have operated alongside France's air force in a combined operation against an hidden munitions depot in Syrian territory operated by the IS group, according to the UK's MoD.
The facility, located using reconnaissance, was assessed as containing munitions and bombs, the statement said, and was positioned in mountains just above the ancient city of Palmyra in Syria's central region.
"Our fighter planes employed precision-guided Paveway IV munitions to hit a number of entry passages leading to the facility... preliminary assessments suggest the objective was successfully hit," the MoD said.
There was no evidence of any harm to civilians in the strike late on Saturday and all the aircraft returned safely, the defence officials confirmed.
The Typhoon fighters were backed up by a Voyager aerial refuelling aircraft.
The Islamic State group - also known as ISIS - enforced militant control over large swathes of Iraq and Syria until 2019.
"This action underscores our UK leadership, and commitment to operate in unison with our allies, to eradicate any revival of the terrorist group and their harmful and extremist ideologies in the Middle East," UK Defence Secretary John Healey remarked.
RAF aircraft have conducted surveillance missions over Syrian airspace to "prevent any efforts to regroup" of Islamic State subsequent to its defeat at the climactic battle in Baghuz in 2019, the ministry said.
"I want to thank the personnel of the UK armed forces who took part in this operation for their expertise and their valour," Healey said. "Including them were a great many UK service members on duty over Christmas and New Year. This mission, to eliminate dangerous terrorists who endanger our safety, shows how UK forces are always on standby, throughout the year, ensuring Britain's security domestically and powerful internationally."
Last December, the US military executed what it called a "major assault" targeting IS targets in the country, subsequent to an attack resulted in the deaths of two US servicemembers and a civilian interpreter in the Palmyra area.
The UN says Daesh still has roughly 5-7 thousand militants in both countries.
